Sunday, 17 January, 2021
Home Health Calcium-rich salt solution FEND can reduce aerosols released by COVID-19 patients by...

Calcium-rich salt solution FEND can reduce aerosols released by COVID-19 patients by upto 98%, shows study

It was additional discovered that whereas masks have been in a position to scale back the big particles FEND, made by Boston-based know-how startup Sensory Cloud, was more practical in lowering the smaller particles

Representational picture. Unsplash/@unitednations

A COVID-19 affected person can generate infectious aerosols whereas sneezing, coughing and even singing. Aerosols are tiny droplets which can be believed to journey as much as six ft within the air and trigger an infection after they are available contact with a mucous membrane of a wholesome particular person. So as to management the unfold of COVID-19, folks have been requested to put on three-layered masks (surgical masks, N-95 masks or selfmade face masks) and preserve bodily distance.

Since masks can solely forestall transmission to a sure diploma, scientists have additionally steered using oral and nasal povidone-iodine, along with sporting masks, to cut back viral load within the nostril and throat, thus minimising the danger of transmission.

In a latest paper revealed within the Molecular Frontiers Journal, scientists have found a more practical means of eradicating aerosols from the nasal passage through the use of a calcium-rich saline answer. The scientists performed three completely different research to succeed in their conclusions.

First research: Utilizing FEND in opposition to aerosols

FEND is a drug-free nasal saline answer made up of calcium chloride and sodium chloride blended in distilled water. The answer, made by Boston-based know-how startup Sensory Cloud, is believed to cut back the contaminated airborne particles from airways.

Researchers from Cambridge and Massachusetts assessed the impact of nasal inhalation of FEND on exhaled aerosol in a research which included 76 individuals at No Evil Meals in Asheville, North Carolina.

The individuals have been divided into three classes on the premise of the quantity of aerosols exhaled; individuals who exhaled better than 850 particles per litre of air, those that exhaled 250 to 850 particles per litre and people who exhaled lower than 250 particles per litre of air.

Earlier than these individuals got FEND, the scientists discovered that the primary two classes of individuals have been super-spreaders as they contributed to 80 % of the entire exhaled particles produced. Additionally, out of those super-spreaders, those who exhaled over 850 particles per litre of air contributed to 64 % of the general aerosol manufacturing.

All of the 76 individuals got FEND within the type of a mist of 9 to 10-micron diameter droplets with the assistance of a hand-held mister.

The outcomes of the research confirmed that after giving FEND, there was an 84 % lowered aerosol exhalation within the individuals who have been earlier exhaling over 850 particles. Additionally, the general exhaled aerosols lowered by 78 % within the super-spreader group.

Second research: Use of FEND in lowering aerosols in a COVID-positive affected person

The second research was performed to search out out the impact of FEND on the lowering aerosol launch in a bunch of 4 folks dwelling in the identical home, which included a 51-year-old girl with COVID-19, her husband (54 years) and two youngsters (14 and 16 years). Within the research, the scientists examined the household for 5 days, ranging from eight days after COVID-19 signs began to look.

On Day 8, the COVID-19 affected person self-administered FEND and examined the exhalation of aerosols. It was discovered that the quantity of aerosols lowered considerably for the next 4 hours. The affected person additional self-administered FEND on the ninth and 10th day and located that the aerosol ranges lowered to common baseline ranges which can be seen in a COVID-19-negative affected person.

Third research: Use of FEND in opposition to surgical masks 

Within the third research, scientists in contrast using FEND in opposition to surgical masks in 12 youngsters and adults. Out of those 12 individuals, three have been discovered to be super-spreaders.

Use of FEND lowered the exhaled particles in two of the three super-spreaders by 98 % and 82 %, respectively, whereas it was lowered by 93 % and 76 % by means of masks.

It was additional discovered that masks have been in a position to scale back the big particles whereas FEND was more practical in lowering the smaller particles.


The scientists concluded that FEND may be an efficient addition to the current COVID-19 safety measures akin to sporting masks, sustaining social distance and washing palms. FEND can enhance the efficacy of masks, which assist in stopping the entry of the virus into the airways and lungs.

For extra info, learn our article on COVID-19: Droplet transmission.

At The Press Reporter, researchers and journalists work with medical doctors to deliver you info on all issues well being.

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