Tuesday, 22 June, 2021
Home Health Covishield produced more antibodies than Covaxin, finds preliminary study

Covishield produced more antibodies than Covaxin, finds preliminary study

The research, which is a preprint and has not been peer-reviewed, shouldn’t be used to information medical apply. Nonetheless, it claimed that seropositivity charges to anti-spike antibodies had been considerably increased in Covishield recipients

A well being employee administers a covid-19 vaccine to a a person throughout a particular vaccination drive held within the premises of a authorities faculty in Hyderabad, India, Sunday, Could 30, 2021. (AP Photograph/Mahesh Kumar A.)

New Delhi: Covishield vaccine produced extra antibodies than Covaxin, in accordance with the coronavirus Vaccine-induced Antibody Titre (COVAT) preliminary research involving healthcare employees (HCW) who’ve obtained each doses of both of the 2 vaccines.

Seropositivity charges to anti-spike antibodies had been considerably increased in Covishield recipients in comparison with Covaxin after the primary dose, the research claimed.

The research is a preprint and has not been peer-reviewed, so shouldn’t be used to information medical apply.

It mentioned that each vaccines – Covishield and Covaxin – elicited a very good response after two doses, however seropositivity fee and median anti-spike antibody had been considerably increased in Covishield.

“Amongst the 552 HCW (325 Male, 227 Feminine), 456 and 96 obtained the primary dose of Covishield and Covaxin respectively. General, 79.three p.c confirmed seropositivity after the primary dose. Responder fee and median (IQR) rise in anti-spike antibody had been considerably increased in Covishield vs. Covaxin recipient (86.eight vs. 43.eight p.c; 61.5 vs. 6 AU/ml; each p<0.001),” the research mentioned.

The research concerned these healthcare employees who’ve been administered both of the 2 vaccines Covishield and Covaxin and are with or with out previous historical past of SARS-CoV-2 an infection.

“This ongoing, Pan-India, Cross-sectional, coronavirus Vaccine-induced Antibody Titre (COVAT) research is being carried out amongst HCW, with or with out previous historical past of SARS-CoV-2 an infection. SARS-CoV-2 anti-spike binding antibody is being assessed quantitatively at four-time factors between 21 days or extra after the primary dose to six months after the second dose,” the research mentioned.

Nonetheless, the conclusion of the research mentioned that each the vaccines have proven elicited good immune response.

“Whereas each vaccines elicited immune response, seropositivity charges to anti-spike antibody had been considerably increased in Covishield recipient in comparison with Covaxin after the primary dose. Ongoing COVAT research will additional enlighten the immune response between two vaccines after the second dose,” it mentioned.

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