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Home Health Johnson & Johnson’s COVID-19 vaccine differs considerably from Pfizer’s, Moderna’s

Johnson & Johnson’s COVID-19 vaccine differs considerably from Pfizer’s, Moderna’s

JnJ’s vaccine seems to be much less susceptible than Pfizer-BioNTech’s and Moderna’s, to set off the sorts of uncomfortable side effects that require monitoring.

A well being employee prepares a vaccine injection for administration. Picture credit score: UNICEF/Nahom Tesfaye

A 3rd efficient weapon was added to America’s arsenal towards the coronavirus Saturday when the Meals and Drug Administration granted emergency use authorization for a vaccine developed by Johnson & Johnson. The corporate stated it could begin transport tens of millions of doses early this week and would offer the USA with 100 million doses by the top of June. Along with 600 million doses of the nation’s first two approved vaccines, made by Pfizer-BioNTech and Moderna, which can be as a result of be delivered over the following 4 months, that should be sufficient to cowl each American grownup who desires to be vaccinated.

The brand new vaccine differs markedly from the 2 already in use in the USA. Right here is how they evaluate.

One shot as an alternative of two

The Johnson & Johnson vaccine is run in a single shot, whereas the Pfizer-BioNTech and Moderna vaccines are given in two pictures a number of weeks aside.

Johnson  Johnsons COVID19 vaccine differs considerably from Pfizers Modernas

Vial of the Johnson & Johnson COVID-19 vaccine. Picture: Johnson & Johnson

How J&J’s COVID-19 shot works

The Johnson & Johnson vaccine makes use of a special methodology to prime the physique to combat off COVID-19 : a viral vector known as Advert26. Viral vectors are frequent viruses which have been genetically altered in order that they don’t trigger sickness however can nonetheless trigger the immune system to construct up its defenses. The Pfizer-BioNTech and Moderna vaccines use messenger RNA to do this.

How nicely it really works

The Johnson & Johnson vaccine is rated as extremely efficient at stopping critical sickness and loss of life, because the Pfizer-BioNTech and Moderna vaccines are. It’s also very efficient at stopping milder sickness, although a bit much less so than these two. It seems to do nicely towards the extremely contagious B.1.351 variant, first recognized in South Africa, that has given not less than one different vaccine candidate bother.

Storage and dealing with

The Johnson & Johnson vaccine doesn’t need to be saved at extraordinarily low temperatures just like the Pfizer-BioNTech vaccine. It could safely be stored in an odd fridge for 3 months, for much longer than the Moderna vaccine, which spoils after a month if not stored frozen.

Unintended effects

The Johnson & Johnson vaccine seems to be much less susceptible than the Pfizer-BioNTech and Moderna vaccines to set off the sorts of uncomfortable side effects that require monitoring after the injection, which can make it extra appropriate to be used at drive-thru vaccination websites. There have been reviews that uncomfortable side effects are typically felt extra strongly after second doses, which the Johnson & Johnson vaccine doesn’t require.

Patrick J. Lyons. c.2021 The New York Instances Firm

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