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Pfizer, Oxford COVID-19 vaccines reduces severity of the disease in elderly: pre-print study

Symptomatic COVID-19 infections in these 70+ years of age additionally decreased, three weeks after a single shot of both vaccine was given.

The Pfizer and Oxford-AstraZeneca vaccines for COVID-19 are extremely efficient in decreasing extreme coronavirus an infection amongst individuals aged 70 years and above, in accordance with a examine. The analysis, posted as a pre-print and but to be peer-reviewed, estimated the impact of each the COVID-19 vaccines on laboratory confirmed symptomatic illness in people aged 70 years or older in England. The researchers, together with these from Public Well being England (PHE), in contrast the speed of hospitalisation and deaths in confirmed COVID-19 sufferers aged over 80 who have been vaccinated greater than 14 days earlier than testing constructive, with unvaccinated circumstances.

Knowledge means that within the over 80s, a single dose of both vaccine is greater than 80 % efficient at stopping hospitalisation, round three to four weeks after the jab, PHE mentioned in an announcement. Proof for the Pfizer vaccine means that it results in 83 % discount in deaths from COVID-19 , it mentioned.

The info additionally exhibits symptomatic infections in over 70s decreased from round three weeks after one dose of each vaccines.

Pfizer Oxford COVID19 vaccines reduces severity of the disease in elderly preprint study

A nurse holds a vial of the Pfizer-BioNTech COVID-19 vaccine at Man’s Hospital in London, Tuesday, Dec. 8, 2020, because the U.Ok. well being authorities rolled out a nationwide mass vaccination program. Picture credit score: AP Photograph/Frank Augstein

“Vaccination with both a single dose of Pfizer or Oxford-AstraZeneca COVID-19 vaccination was related to a big discount in symptomatic SARS-CoV2 constructive circumstances in older adults with even larger safety in opposition to extreme illness,” mentioned the authors of the examine, including each the vaccines present related results.

They mentioned the safety was maintained throughout over six weeks of follow-up, and there’s a clear impact of each the vaccines in opposition to the UK variant of concern.

Consultants say the brand new evaluation provides to rising proof that the vaccines are working, and are extremely efficient in defending individuals in opposition to extreme sickness, hospitalisation and demise.

“This provides to rising proof displaying that the vaccines are working to cut back infections and save lives,” Mary Ramsay, PHE Head of Immunisation, mentioned within the assertion.

“Whereas there stays rather more information to comply with, that is encouraging and we’re more and more assured that vaccines are making an actual distinction,” Ms Ramsay mentioned.

Nevertheless, she cautioned that the safety shouldn’t be full and it’s not identified but how a lot these vaccines will scale back the chance of somebody passing the coronavirus onto others.

“Even if in case you have been vaccinated, it’s actually necessary that you simply proceed to behave like you’ve the virus, practise good hand hygiene and keep at house,” Ms Ramsay added.

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